Products for Research Use Only

CDK8-IN-13

CAT: 0931-T72029-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T72029-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
918523-75-8
Target
Apoptosis, CDK
Related Pathways
Apoptosis, Cell Cycle/Checkpoint
Purity
0.9928
Bioactivity
CDK8-IN-13 is a CDK8 inhibitor (IC50: 51.9 nM) with potent, selective and oral activity. CDK8-IN-13 induces apoptosis and reduces the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 exhibits anti-tumour activity.
Smiles
C(N)(=O)C=1C=C(C=2C=C3C(=NC2)NC=C3)C=CC1
Molecular Formula
C14H11N3O
Molecular Weight
237.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C