CDK8-IN-13

• Target :

  Apoptosis|||CDK

• Related Pathways :

  Apoptosis|||Cell Cycle/Checkpoint

• Purity :

  0.9928

• Bioactivity :

  CDK8-IN-13 is a CDK8 inhibitor (IC50: 51.9 nM) with potent, selective and oral activity. CDK8-IN-13 induces apoptosis and reduces the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 exhibits anti-tumour activity.

• Smiles :

  C(N)(=O)C=1C=C(C=2C=C3C(=NC2)NC=C3)C=CC1

• Molecular Formula :

  C14H11N3O

• Molecular Weight :

  237.26

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  918523-75-8