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CDK8-IN-19

CAT: 931-T210596-01Size: 10 mgDry Ice: NoHazardous: No
10 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PI3K|||CDK
Related Pathways
PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint
Bioactivity
CDK8-IN-19 (Compound 3d) is a CDK8 inhibitor with an IC50 of 25.08 nM. It exhibits broad-spectrum anticancer activity, showing effectiveness against leukemia, melanoma, and breast cancer, while demonstrating no significant cytotoxicity to normal Vero cells (mean IC50 values are 2.87, 3.65, 3.79, and 45.48 ?M, respectively) .
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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