CDK8-IN-11

• Target:

  CDK|||Wnt/beta-catenin

• Related Pathways:

  Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||Stem Cells

• Purity:

  0.9974

• Bioactivity:

  CDK8-IN-11 is a selective and potent CDK8 inhibitor that shows antiproliferative activity in colon cancer cell lines, inhibiting WNT/?-catenin activation and TCF family transcriptional activity, inducing G1-phase arrest in HCT-116 cells, useful for colon cancer research.

• Smiles:

  O=C(NC1=CC=C(OC2=CN=C(N)C=C2)C=C1)NC3=CC=CC(=C3)C(F)(F)F

• Molecular Formula:

  C19H15F3N4O2

• Molecular Weight:

  388.34

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2839338-28-0