CDK8-IN-11

• Target :

  CDK|||Wnt/beta-catenin

• Related Pathways :

  Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||Stem Cells

• Purity :

  0.9974

• Bioactivity :

  CDK8-IN-11 is a selective and potent CDK8 inhibitor that shows antiproliferative activity in colon cancer cell lines, inhibiting WNT/?-catenin activation and TCF family transcriptional activity, inducing G1-phase arrest in HCT-116 cells, useful for colon cancer research.

• Smiles :

  O=C(NC1=CC=C(OC2=CN=C(N)C=C2)C=C1)NC3=CC=CC(=C3)C(F)(F)F

• Molecular Formula :

  C19H15F3N4O2

• Molecular Weight :

  388.34

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2839338-28-0