Verubecestat TFA

• Target :

  Others|||Beta-Secretase

• Related Pathways :

  Others|||Neuroscience

• Bioactivity :

  Verubecestat TFA, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat TFA is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat TFA reduced A? cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients.

• Smiles :

  OC(=O)C(F)(F)F.CN1C(=N)N[C@@](C)(CS1(=O)=O)c1cc(NC(=O)c2ccc(F)cn2)ccc1F

• Molecular Formula :

  C19H18F5N5O5S

• Molecular Weight :

  523.435

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2095432-65-6