Verubecestat TFA

• Target:

  Others|||Beta-Secretase

• Related Pathways:

  Others|||Neuroscience

• Bioactivity:

  Verubecestat TFA, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat TFA is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat TFA reduced A? cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients.

• Smiles:

  OC (=O) C (F) (F) F.CN1C (=N) N[C@@] (C) (CS1 (=O) =O) c1cc (NC (=O) c2ccc (F) cn2) ccc1F

• Molecular Formula:

  C19H18F5N5O5S

• Molecular Weight:

  523.435

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2095432-65-6