Verubecestat (Standard)

CAT: 0804-HY-16759R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-16759R-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Verubecestat (Standard) is the analytical standard of Verubecestat. This product is intended for research and analytical applications. Verubecestat (MK-8931) is an orally active, high-affinity BACE1 and BACE2 inhibitor with Ki values of 2.2 nM and 0.38 nM. Verubecestat effectively reduces Aβ40 and has the potential for Alzheimer's Disease[1][2].
CAS Number
[1286770-55-5]
UNSPSC
12352100
Target
Beta-secretase; Reference Standards
Related Pathways
Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
O=C(C1=NC=C(F)C=C1)NC2=CC=C(F)C([C@@](C3)(C)N=C(N)N(C)S3(=O)=O)=C2
Molecular Formula
C17H17F2N5O3S
Molecular Weight
409.41
References & Citations
[1]Yan R, et al. Stepping closer to treating Alzheimer's disease patients with BACE1 inhibitor drugs. Transl Neurodegener. 2016 Jul 14;5:13.|[2]Scott JD, et al. Discovery of the 3-Imino-1,2,4-thiadiazinane 1,1-Dioxide Derivative Verubecestat (MK-8931) -A β-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor for the Treatment of Alzheimer'sDisease. Med Chem. 2016 Dec 8;59 (23) :10435-10450.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-16759-01Verubecestat
HY-16759A-01Verubecestat (TFA)
HY-16759BVerubecestat (tosylate)
HY-N2192RSwertianolin (Standard)
HY-B2138R-01Ethopabate (Standard)
HY-131105RCimbuterol (Standard)
HY-108560R-01(+) -Fluprostenol (Standard)
HY-121765R-01Dacisteine (Standard)
HY-B0828RTriazophos (Standard)
HY-N0472R-01Geraniin (Standard)

Alternative Products

CatalogName
MF-0012970-01Verubecestat
MBS5814404Verubecestat TFA
MF-0144561-01Verubecestat tosylate
A16113-5Verubecestat 5mg
A16113-10Verubecestat 10mg
A16113-50Verubecestat 50mg
MBS579527Verubecestat (MK-8931)
330124Verubecestat free base

Popular Products