JHU-58

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  JHU-58 is a novel dipeptide MrgC agonist. JHU-58 inhibited both mechanical and heat hypersensitivity in rats after an L5 spinal nerve ligation (SNL) . JHU58 attenuated the evoked excitatory postsynaptic currents in substantia gelatinosa (SG) neurons in wild-type mice, but not in Mrg knockout mice, after peripheral nerve injury.

• Smiles:

  C([C@H](C(N[C@@H](CC1=CC=CC=C1)C(N)=O)=O)N)C2=CC=C(NC(=N)N)C=C2

• Molecular Formula:

  C19H24N6O2

• Molecular Weight:

  368.43

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1632140-61-4