JHU-083

• Target:

  Glutaminase|||RAAS

• Related Pathways:

  Proteases/Proteasome|||Endocrinology/Hormones

• Purity:

  0.9953

• Bioactivity:

  JHU-083 is an orally available, blood-brain barrier-crossing, selective glutaminase antagonist that improves cognitive performance and normalizes abnormal hippocampal glutaminase activity in APOE4 mice.

• Smiles:

  [C@H](NC([C@H](CC(C)C)N)=O)(CCC(C=[N+]=[N-])=O)C(OCC)=O

• Molecular Formula:

  C14H24N4O4

• Molecular Weight:

  312.37

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1998725-11-3