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APS-2-79

CAT: 0931-T70004-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T70004-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2002381-25-9
Target
Others, MEK
Related Pathways
MAPK, Others
Bioactivity
APS-2-79, a KSR-dependent MEK antagonist, disrupts ATP (biotin) binding within the KSR2-MEK1 complex, achieving an inhibitory concentration (IC50) of 120 nM. This action stabilizes the KSR inactive state and antagonizes oncogenic Ras-MAPK signaling.
Smiles
COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3C)c2cc1OC
Molecular Formula
C23H21N3O3
Molecular Weight
387.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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B7820-100APS-2-79
C18168-100mgAPS-2-79 HCl
CFD38131-01APS-2-79 hydrochloride
A16231-100APS-2-79 100mg
A16231-5APS-2-79 5mg

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