RK-0080552

CAT: 0931-T206998-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T206998-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
313527-11-6
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
RK-0080552 (RK-552) is an inhibitor of the NSD2 histone methyltransferase. It demonstrates significant cytotoxicity against multiple myeloma (MM) cells harboring the t (4;14) translocation. This compound suppresses the IRF4 gene and decreases the dimethylation of histone H3 at lysine 36. RK-0080552 holds promise for research in hematologic malignancies.
Smiles
O=C1C=2N=NC(=NC2C=3C=CC=CC13)C4=NON=C4N
Molecular Formula
C12H6N6O2
Molecular Weight
266.215
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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