MK-0626

• Target :

  Glucagon Receptor|||AMPK

• Related Pathways :

  GPCR/G Protein|||PI3K/Akt/mTOR signaling|||Chromatin/Epigenetic

• Purity :

  >99.99%

• Bioactivity :

  MK-0626 is an orally available dipeptidyl peptidase IV (DPP-4) inhibitor that attenuates hepatic steatosis and accumulation by enhancing AMPK activity.MK-0626 attenuates TAC-induced diabetic pancreatic islet injury by restoring the expression of GLP-1R.MK-0626 is able to increase circulating endothelial progenitor cell numbers and endothelial-type nitric oxide synthase expression by promoting neoangiogenesis.

• Smiles :

  [C@H]([C@@H](C(=O)N1CC(F)(F)CC1)N)(C(N(C)C)=O)C2=CC=C(C=C2)C3=CN4C(C=C3)=NC=N4

• Molecular Formula :

  C22H24F2N6O2

• Molecular Weight :

  442.46

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  690257-74-0