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MK-0626

CAT: 0931-T68863-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T68863-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
690257-74-0
Target
Glucagon Receptor|||AMPK
Related Pathways
GPCR/G Protein|||PI3K/Akt/mTOR signaling|||Chromatin/Epigenetic
Purity
>99.99%
Bioactivity
MK-0626 is an orally available dipeptidyl peptidase IV (DPP-4) inhibitor that attenuates hepatic steatosis and accumulation by enhancing AMPK activity.MK-0626 attenuates TAC-induced diabetic pancreatic islet injury by restoring the expression of GLP-1R.MK-0626 is able to increase circulating endothelial progenitor cell numbers and endothelial-type nitric oxide synthase expression by promoting neoangiogenesis.
Smiles
[C@H]([C@@H](C(=O)N1CC(F)(F)CC1)N)(C(N(C)C)=O)C2=CC=C(C=C2)C3=CN4C(C=C3)=NC=N4
Molecular Formula
C22H24F2N6O2
Molecular Weight
442.46
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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