Products for Research Use Only

PCSK9-IN-11

CAT: 0931-T67776-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T67776-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, LDLR
Related Pathways
Metabolism, Others
Purity
0.991
Bioactivity
PCSK9-IN-11 (compound 5r) is a potent PCSK9 inhibitor with oral activity, exhibiting inhibitory activity on PCSK9 transcription in HepG2 cells (IC50 = 5.7 μM) and capable of increasing LDL receptor (LDLR) protein levels. PCSK9-IN-11 is applicable for atherosclerosis research.
Smiles
CN1C(=O)C2=C(N=C(NCCO)N2CC2=C(F)C(Cl)=CC=C2)N(C)C1=O
Molecular Formula
C16H17ClFN5O3
Molecular Weight
381.79
Shipping Conditions
Ice Packs
Storage Temperature
-20°C