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PCSK9-IN-10

CAT: 0931-T72025-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T72025-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
368434-98-4
Target
Serine/threonin kinase, LDLR, Others
Related Pathways
Cell Cycle/Checkpoint, Others, Metabolism
Purity
0.9906
Bioactivity
PCSK9-IN-10, a potent and orally active inhibitor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9), exhibits a half-maximal inhibitory concentration (IC50) of 6.4 μM. By enhancing the expression of Low-Density Lipoprotein Receptor (LDLR) protein and reducing PCSK9 expression, PCSK9-IN-10 effectively decreases atherosclerosis progression. This compound holds promise for hyperlipidemia research applications.
Smiles
COCCNc1nc2n(C)c(=O)n(C)c(=O)c2n1Cc1cccc(OC)c1
Molecular Formula
C18H23N5O4
Molecular Weight
373.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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BA8064-10PCSK9-IN-10
pro-2043PCSK9
048564PCSK9 (Boehringer PCSK9) discontinued
048566PCSK9 (Schering patent PCSK9) discontinued
C00552-1mgAnti-PCSK9 (Boehringer anti-PCSK9)
048565PCSK9 (Merck patent PCSK9) discontinued

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