(S) -DI-87

• Target:

  DNA/RNA Synthesis

• Related Pathways:

  Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

• Purity:

  0.9942

• Bioactivity:

  (S) -DI-87 ((S) -TRE-515) is an isomer of DI-87.DI-87 is a novel and orally available dCK (deoxycytidine kinase) inhibitor with good in vitro activity and low protein binding.DI-87 binds to dCK and prevents the phosphorylation of deoxycytidine by dCK, resulting in a reduction in dNTP production and cell cycle arrest (especially in S phase) . When combined with thymidine, DI-87 significantly inhibits tumor growth.

• Smiles:

  [C@H] (SC=1N=C (N) C=C (N) N1) (C) C=2N=C (SC2C) C3=CC (OCCN4CCOCC4) =C (OC) C=C3

• Molecular Formula:

  C23H30N6O3S2

• Molecular Weight:

  502.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2107280-58-8