NLRP3 modulator 8

CAT: 0931-MF-0119530-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0119530-01Size:10 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
3069891-88-6
Target
NOD
Related Pathways
Immunology/Inflammation|||NF-?B
Bioactivity
NLRP3 modulator 8 (Compound 14) is an NLRP3 regulator that can significantly degrade the NEK7 protein (DC50 = 9 nM) . In macrophages, NLRP3 modulator 8 can inhibit the activity of caspase-1 in a dose-dependent manner and reduce the release of IL-1? triggered by the activation of the NLRP3 inflammasome. NLRP3 modulator 8 is applicable for the research of various diseases, including autoinflammatory and autoimmune diseases, neurodegenerative diseases, as well as cardiovascular and metabolic-related diseases, etc.
Smiles
FC1=CN=C(C(C)(C)C(NCC2=CC(Cl)=C(C3C(NC(CC3)=O)=O)C(Cl)=C2)=O)N=C1
Molecular Formula
C20H19Cl2FN4O3
Molecular Weight
453.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
MF-0138955-01NLRP3-IN-8
MF-0114573-01Sirtuin modulator 8
MF-0097868-01β-Catenin modulator-8
MF-0062763-01AMPA receptor modulator-8
MF-0115187-01GABAA receptor modulator-8
MF-0120783-01IL-17 modulator 8
MF-0115181-01Nav1.8 modulator 1
MF-0152755NLRP3 modulators 1
MF-0093695-01NLRP3-IN-9
MF-0146479-01NLRP3-IN-14

Alternative Products

CatalogName
HY-177433NLRP3 modulator 8
HY-103715NLRP3 modulator 1
QY-E06005Human NLRP3 Inflammasome (NLRP3)
MBS8565269-01NLRP3
MBS8500849-01NLRP3 Antibody
M35555-01NLRP3-IN-10
HY-149604-01NLRP3-IN-21
HY-163497NLRP3-IN-38

Popular Products