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GDC-0152-acetamide

CAT: 0931-T212179-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T212179-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis, IAP
Related Pathways
Apoptosis
Bioactivity
GDC-0152-acetamide is a pan-antagonist of apoptosis inhibiting proteins (IAPs) . It induces the autoubiquitination and subsequent degradation of cIAP1/2, activates the non-canonical NF-κB pathway, and promotes the secretion of TNF-α, leading to apoptosis in tumor cells. GDC-0152-acetamide holds potential for research in ERα-positive breast cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-175446GDC-0152-acetamide
A4224-50GDC-0152
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