GDC-0152-acetamide
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
GDC-0152-acetamide
Target:
Apoptosis|||IAPRelated Pathways:
ApoptosisBioactivity:
GDC-0152-acetamide is a pan-antagonist of apoptosis inhibiting proteins (IAPs) . It induces the autoubiquitination and subsequent degradation of cIAP1/2, activates the non-canonical NF-?B pathway, and promotes the secretion of TNF-?, leading to apoptosis in tumor cells. GDC-0152-acetamide holds potential for research in ER?-positive breast cancer.Shipping Conditions:
Cool packStorage Temperature:
-20°C