GDC-0339

• Target:

  Pim

• Related Pathways:

  Chromatin/Epigenetic|||JAK/STAT signaling

• Bioactivity:

  GDC-0339 is discovered as a potential treatment of multiple myeloma. GDC-0339 is an orally bioavailable and well-tolerated inhibitor of the pan-Pim kinase (Kis: 0.03 nM, 0.1 nM, and 0.02 nM for Pim1, Pim2, and Pim3, respectively) .

• Smiles:

  Cn1ncc(NC(=O)c2nc(sc2N)-c2c(F)cccc2F)c1N1CC[C@@H](N)[C@H](F)CC1

• Molecular Formula:

  C20H22F3N7OS

• Molecular Weight:

  465.5

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1428569-85-0