GDC-0349

• Target :

  PI3K|||Autophagy|||mTOR

• Related Pathways :

  Autophagy|||PI3K/Akt/mTOR signaling

• Purity :

  0.9898

• Bioactivity :

  GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3K? and other 266 kinases. Phase 1.

• Smiles :

  CCNC(=O)Nc1ccc(cc1)-c1nc2CN(CCc2c(n1)N1CCOC[C@@H]1C)C1COC1

• Molecular Formula :

  C24H32N6O3

• Molecular Weight :

  452.55

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1207360-89-1