XL-3156

• Target :

  CGAS

• Related Pathways :

  Immunology/Inflammation

• Bioactivity :

  XL-3156 is a potent, selective, and cross-species inhibitor of cGAS. It simultaneously occupies allosteric and orthosteric sites, stabilizing the closed conformation of the activation loop to inhibit the interaction and phase separation of cGAS with DNA. XL-3156 is applicable for research into autoimmune diseases and inflammation.

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C