XL-126

• Target:

  Epigenetic Reader Domain

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  XL-126 (Compound 33) is a potent BD1-selective BET inhibitor with a Kd of 8.9 nM. Its selectivity for BD1 enables it to protect platelets and exhibit significant anti-inflammatory effects.

• Smiles:

  O=C1C (=CC (=CN1C) C=2C=C (NS (=O) (=O) CC) C=3C=CN (C3C2) C (C4=NC=CC=C4) (C5=NC=CC=C5) C) NC6CCNCC6

• Molecular Formula:

  C33H37N7O3S

• Molecular Weight:

  611.76

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3033576-12-1