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GCN2 activator-1

CAT: 0931-T211805-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211805-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
315705-10-3
Target
PERK
Related Pathways
Apoptosis
Bioactivity
GCN2 activator-1 (Compound 20) is a GCN2 activator that binds to the ATP pocket of GCN2 and activates it in a GCN1-independent manner. It can stimulate the integrated stress response (ISR) in cells and inhibits PKR with an IC50 of 3.75 μM. GCN2 activator-1 is utilized for research on pulmonary veno-occlusive disease (PVOD) .
Smiles
N=1C=CC=NC1NC2=NC(=CS2)C=3SC(=NC3C)N
Molecular Formula
C11H10N6S2
Molecular Weight
290.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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HY-W319647-01GCN2 activator-1
BA4093-5.1GCN2-IN-1
A20412-500GCN2-IN-1 500mg
A20412-5GCN2-IN-1 5mg
A20412-50GCN2-IN-1 50mg
A20412-25GCN2-IN-1 25mg
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A20412-10GCN2-IN-1 10mg

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