Nav1.1 activator 1

CAT: 0931-T12179-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T12179-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2332897-85-3

Target

Sodium Channel

Related Pathways

Membrane transporter/Ion channel

Bioactivity

Nav1.1 activator 1 (compound 4) is an effective Nav1.1 agonist with blood-brain barrier permeability, exhibiting significant selectivity for Nav1.2, Nav1.5, and Nav1.6. It increases the decay time constant of Nav1.1 at 0.03 μM current and can be used for studying central nervous system disorders.

Smiles

C(NC=1C=CC(C(C)C)=NC1)(=O)C=2C(=CC=NC2N3C[C@@H](F)CC3)C4=C(F)C=CC(F)=C4

Molecular Formula

C24H23F3N4O

Molecular Weight

440.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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