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VEGFR-2-IN-71

CAT: 0931-T211603-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211603-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Microtubule Associated, Apoptosis, VEGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Apoptosis, Cytoskeletal Signaling
Bioactivity
VEGFR-2-IN-71 is a dual inhibitor of VEGFR2/tubulin. It suppresses tumor cell proliferation, induces apoptosis and cell cycle arrest, and inhibits angiogenesis in the chicken embryo chorioallantoic membrane (CAM) model. By targeting VEGFR2 and tubulin, VEGFR-2-IN-71 hinders tumor growth in the HGC-27 xenograft model. It exhibits low oral bioavailability in rats and is applicable in cancer research.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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