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TD-6301

CAT: 0931-T211557-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211557-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
690999-15-6
Target
AChR
Related Pathways
Neuroscience
Bioactivity
TD-6301 is a bladder-selective M2/4 muscarinic receptor antagonist. It binds with high selectivity and blocks M2/4 muscarinic receptors, exhibiting particularly strong affinity for the human M2 receptor (Ki= 0.36 nM) . TD-6301 inhibits volume-induced bladder contraction (ID50= 0.075 mg/kg) and is applicable for studying overactive bladder conditions.
Smiles
C(C(N)=O)([C@H]1CN(CCCCCCCN(C(C)C)C2CCN(CC=3C(OC)=CC=NC3)CC2)CC1)(C4=CC=CC=C4)C5=CC=CC=C5
Molecular Formula
C40H57N5O2
Molecular Weight
639.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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