TD-6301

• Target :

  AChR

• Related Pathways :

  Neuroscience

• Bioactivity :

  TD-6301 is a bladder-selective M2/4 muscarinic receptor antagonist. It binds with high selectivity and blocks M2/4 muscarinic receptors, exhibiting particularly strong affinity for the human M2 receptor (Ki= 0.36 nM) . TD-6301 inhibits volume-induced bladder contraction (ID50= 0.075 mg/kg) and is applicable for studying overactive bladder conditions.

• Smiles :

  C(C(N)=O)([C@H]1CN(CCCCCCCN(C(C)C)C2CCN(CC=3C(OC)=CC=NC3)CC2)CC1)(C4=CC=CC=C4)C5=CC=CC=C5

• Molecular Formula :

  C40H57N5O2

• Molecular Weight :

  639.91

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  690999-15-6