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TD-0212

CAT: 0931-T13125-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T13125-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1073549-10-6
Target
Neprilysin, RAAS, Others
Related Pathways
Endocrinology/Hormones, Metabolism, Others
Bioactivity
TD-0212 is an orally active dual pharmacology antagonist of angiotensin II type 1 receptor (AT1) and inhibitor of neprilysin (NEP) (pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP) .
Smiles
C(N1C(CNC([C@H](CC(C)C)S)=O)=C(CC)N=C1OCC)C2=C(F)C=C(C=C2)C3=C(C(O)=O)C=CC=C3
Molecular Formula
C28H34FN3O4S
Molecular Weight
527.65
Shipping Conditions
Ice Packs
Storage Temperature
-20°C