TD-0212

• Target:

  Neprilysin|||RAAS|||Others

• Related Pathways:

  Endocrinology/Hormones|||Metabolism|||Others

• Bioactivity:

  TD-0212 is an orally active dual pharmacology antagonist of angiotensin II type 1 receptor (AT1) and inhibitor of neprilysin (NEP) (pKi of 8.9 for AT1 and a pIC50 of 9.2 for NEP) .

• Smiles:

  C(N1C(CNC([C@H](CC(C)C)S)=O)=C(CC)N=C1OCC)C2=C(F)C=C(C=C2)C3=C(C(O)=O)C=CC=C3

• Molecular Formula:

  C28H34FN3O4S

• Molecular Weight:

  527.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1073549-10-6