Products for Research Use Only

LO-3-63

CAT: 0931-T211507-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T211507-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
E1/E2/E3 Enzyme, CDK
Related Pathways
Ubiquitination, Cell Cycle/Checkpoint
Bioactivity
LO-3-63 is a Ribociclib analogue featuring a truncated fumaramide group and acts as a CDK4/6 degrader with PROTAC properties. It degrades CDK4/6 in cells via a CUL4DCAF16-dependent pathway.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C