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LO-3-61

CAT: 0013-GTR19263720-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263720-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LO-3-61 is a JQ-1 analog featuring a truncated fumarylamide group, classified as a BRD4 degrader with PROTAC (protein degradation targeting chimera) properties. It promotes the degradation of both long and short BRD4 isoforms via a CUL4DCAF16-dependent pathway. In MDA-MB-231 cells, LO-3-61 exhibits selectivity in degrading BRD3 and BRD4.
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery, Protein Biochemistry
Storage Conditions
-20°C
Notes
For research use only.

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