Mtb-IN-10

CAT: 0931-T205277-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T205277-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Antibacterial|||Antibiotic
Related Pathways
Microbiology/Virology
Bioactivity
Mtb-IN-10 (Compound P15) is an Rv1625c/Cya activator that influences the growth of Mycobacterium tuberculosis (Mtb) by modulating cAMP metabolism. It demonstrates an anti-tuberculosis activity with an EC50 of 1.96 µM in Mtb-infected macrophage models and achieves an oral bioavailability of 58.0% when administered orally to mice at 20 mg/kg. Mtb-IN-10 potentially regulates intracellular signaling and disrupts cholesterol metabolism within Mtb, thereby inhibiting bacterial proliferation. It holds promise for tuberculosis (TB) research, particularly targeting multidrug-resistant (MDR-TB) and extensively drug-resistant (XDR-TB) strains of Mtb.
Molecular Formula
C12H14N2O4S2
Molecular Weight
314.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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