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PARP1-IN-39

CAT: 0931-T211022-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211022-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3054988-47-2
Target
PARP
Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic
Bioactivity
PARP1-IN-39 is an inhibitor of PARP1, with an IC50 value of 0.22 nM. In human breast cancer cells, its IC50 is 1.57 nM. PARP1-IN-39 is applicable for studying cancers associated with DNA repair deficiencies, such as breast, ovarian, pancreatic, and prostate cancers, particularly those with BRCA1/2 mutations.
Smiles
O=C(NCC)C1=NC(F)=C(C=C1)N2N=C3C(=C2)CN(C3)CC4=CC=C5C(NC(=O)C6=C(F)C=NN56)=C4F
Molecular Formula
C24H19F3N8O2
Molecular Weight
508.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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