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PARP1-IN-35

CAT: 0931-T204810-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204810-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PARP
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
Bioactivity
PARP1-IN-35 (compound T26) is a selective, orally active PARP1 inhibitor that can cross the blood-brain barrier, with IC50 values of 0.2 nM for PARP1 and 122 nM for PARP2. It exhibits antiproliferative and anticancer activities and holds potential for breast cancer research.
Smiles
CCC1=CC2=C(C=C(C=N2)CN3CCC(=CC3)C4=NC=C(C=C4)C#N)NC1=O
Molecular Formula
C22H21N5O
Molecular Weight
371.435
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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