BRD4-IN-10

• Target:

  Epigenetic Reader Domain

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  BRD4-IN-10 (Compound 31) is a selective BRD4 inhibitor with an IC50 of 13.5 nM. It exhibits anti-inflammatory and anti-fibrotic effects, possesses good metabolic stability, favorable pharmacokinetic properties, and safety. BRD4-IN-10 is suitable for research in kidney fibrosis diseases.

• Smiles:

  O=C1C2(CCN(CC2)C3=NC(NC=4C=C5C(=CC4)N(C)C(=O)[C@@H](C)N5C(C)C)=NC=C3)NC(=O)N1

• Molecular Formula:

  C24H30N8O3

• Molecular Weight:

  478.55

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3051852-76-4