BRD4-IN-10

• Target :

  Epigenetic Reader Domain

• Related Pathways :

  Chromatin/Epigenetic

• Bioactivity :

  BRD4-IN-10 (Compound 31) is a selective BRD4 inhibitor with an IC50 of 13.5 nM. It exhibits anti-inflammatory and anti-fibrotic effects, possesses good metabolic stability, favorable pharmacokinetic properties, and safety. BRD4-IN-10 is suitable for research in kidney fibrosis diseases.

• Smiles :

  O=C1C2(CCN(CC2)C3=NC(NC=4C=C5C(=CC4)N(C)C(=O)[C@@H](C)N5C(C)C)=NC=C3)NC(=O)N1

• Molecular Formula :

  C24H30N8O3

• Molecular Weight :

  478.55

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3051852-76-4