BRD4-IN-5

• Target:

  Epigenetic Reader Domain

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  BRD4-IN-5 (example 51), a potent BRD4 inhibitor, exhibits K i values of 9.7 nM for the BDI_K57-E168 domain and 16.1 nM for the BDII_E352-M457 domain. This compound is utilized in cancer research [1].

• Smiles:

  O(C1=C(C=C(C(NC2CCOC2)=O)C=C1)C=3C4=C(C(=O)N(C)C3)NC=C4)C5=C(F)C=C(F)C=C5

• Molecular Formula:

  C25H21F2N3O4

• Molecular Weight:

  465.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1445993-41-8