Pro-Dasatinib

• Target:

  Src|||Bcr-Abl

• Related Pathways:

  Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis

• Bioactivity:

  Pro-Dasatinib (compound 2j) is an amino acid analogue of Dasatinib and serves as a potent Src/Abl kinase inhibitor. It exhibits antiproliferative activity against K652 leukemia cancer cells, with an IC50 of 0.21 nM.

• Smiles:

  N (C1=CC (N2CCN (C (=O) [C@@H]3CCCN3) CC2) =NC (C) =N1) C=4SC (C (NC5=C (C) C=CC=C5Cl) =O) =CN4

• Molecular Formula:

  C25H29ClN8O2S

• Molecular Weight:

  541.07

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2468065-01-0