Pro-Dasatinib

• Target :

  Src|||Bcr-Abl

• Related Pathways :

  Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||Angiogenesis

• Bioactivity :

  Pro-Dasatinib (compound 2j) is an amino acid analogue of Dasatinib and serves as a potent Src/Abl kinase inhibitor. It exhibits antiproliferative activity against K652 leukemia cancer cells, with an IC50 of 0.21 nM.

• Smiles :

  N(C1=CC(N2CCN(C(=O)[C@@H]3CCCN3)CC2)=NC(C)=N1)C=4SC(C(NC5=C(C)C=CC=C5Cl)=O)=CN4

• Molecular Formula :

  C25H29ClN8O2S

• Molecular Weight :

  541.07

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2468065-01-0