Hydroxymethyl dasatinib

• Target:

  Apoptosis|||Drug Metabolite|||Bcr-Abl|||Src

• Related Pathways:

  Angiogenesis|||Apoptosis|||Metabolism|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors

• Bioactivity:

  Hydroxymethyl dasatinib (M24), a benzylhydroxy metabolite of Dasatinib, demonstrates potent activity with an IC50 value of 46.7 nM in K562 CML cells [1].

• Smiles:

  N (C1=CC (N2CCN (CCO) CC2) =NC (C) =N1) C=3SC (C (NC4=C (CO) C=CC=C4Cl) =O) =CN3

• Molecular Formula:

  C22H26ClN7O3S

• Molecular Weight:

  504.01

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  910297-58-4