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Hydroxymethyl dasatinib

CAT: 0931-T86695-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T86695-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
910297-58-4
Target
Apoptosis, Drug Metabolite, Bcr-Abl, Src
Related Pathways
Angiogenesis, Apoptosis, Metabolism, Cytoskeletal Signaling, Tyrosine Kinase/Adaptors
Bioactivity
Hydroxymethyl dasatinib (M24), a benzylhydroxy metabolite of Dasatinib, demonstrates potent activity with an IC50 value of 46.7 nM in K562 CML cells [1].
Smiles
N(C1=CC(N2CCN(CCO)CC2)=NC(C)=N1)C=3SC(C(NC4=C(CO)C=CC=C4Cl)=O)=CN3
Molecular Formula
C22H26ClN7O3S
Molecular Weight
504.01
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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