RegisterLogin

Dasatinib monohydrate

CAT: 0931-T1448L-01Size: 50 mgDry Ice: NoHazardous: No
CAT#:0931-T1448L-01Size:50 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
863127-77-9
Target
Apoptosis|||Ephrin Receptor|||Autophagy|||Src|||c-Kit|||Bcr-Abl
Related Pathways
Tyrosine Kinase/Adaptors|||Apoptosis|||Autophagy|||Angiogenesis|||Cytoskeletal Signaling
Purity
>99.99%
Bioactivity
Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activities of these kinases. Apparently, because of its less stringent binding affinity for the BCR-ABL kinase, Dasatinib monohydrate has been shown to overcome the resistance to imatinib of chronic myeloid leukemia (CML) cells harboring BCR-ABL kinase domain point mutations.
Smiles
N1cc(sc1Nc1nc(nc(N2CCN(CC2)CCO)c1)C)C(=O)Nc1c(cccc1C)Cl.O
Molecular Formula
C22H28ClN7O3S
Molecular Weight
506.03
Shipping Conditions
Cool pack
Storage Temperature
-20°C

Related Products

CatalogName
T1448-01Dasatinib
T210759-01Pro-Dasatinib
T210801-01Gly-Dasatinib
T22303-01Dasatinib hydrochloride
T86695-01Hydroxymethyl dasatinib
T18595-01Dasatinib carbaldehyde
T10962Dasatinib-d8
T18750-01N-Deshydroxyethyl Dasatinib
T37645-01Dasatinib metabolite M6
T37600-01Dasatinib N-oxide

Alternative Products

CatalogName
MBS384389-01Dasatinib Monohydrate
sc-218081Dasatinib (monohydrate)
A16320-100Dasatinib Monohydrate 100mg
HY-10181BRDasatinib (monohydrate) (Standard)
A16320-50Dasatinib Monohydrate 50mg
A16320-200Dasatinib Monohydrate 200mg
A16320-1000Dasatinib Monohydrate 1000mg
A16320-500Dasatinib Monohydrate 500mg
A16320-10mM-DDasatinib Monohydrate 10mM * 1mL in DMSO
D6690-01Dasatinib

Popular Products