PRMT5-IN-52

• Target:

  Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  PRMT5-IN-52 (Compound 17) is a non-nucleoside inhibitor of protein arginine methyltransferase 5 (PRMT5), demonstrating an inhibition rate of 20.2% at a concentration of 10 ?M. PRMT5-IN-52 exhibits potent antitumor activity and holds potential for research in cancers such as lung, prostate, and colorectal cancer.

• Smiles:

  N=1C=NC=2NC(=CC2C1N)C=3C=CC(OCC=4C=CC=CC4)=CC3

• Molecular Formula:

  C19H16N4O

• Molecular Weight:

  316.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2783961-64-6