CDK9-IN-33

• Target:

  Apoptosis|||CDK

• Related Pathways:

  Cell Cycle/Checkpoint|||Apoptosis

• Bioactivity:

  CDK9-IN-33 (compound C35) is a potent, selective, and orally bioavailable CDK9 inhibitor with IC50 values of 17.44 nM for CDK9, 160 nM for CDK7, 316.30 nM for CDK2, 1771.00 nM for CDK4, and >10000 nM for CDK6. This compound induces apoptosis (cell apoptosis) and reduces the protein expression of RPB1 CTD Ser2, RPB1, and MCL1, exhibiting antitumor activity.

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C