CDK9-IN-19

• Target :

  Others|||CDK

• Related Pathways :

  Others|||Cell Cycle/Checkpoint

• Bioactivity :

  CDK9-IN-19 is a selective and potent CDK9 inhibitor (IC50: 2.0 nM) . CDK9-IN-19 exhibits good anti-proliferative activity in cancer cells, moderate pharmacokinetic properties and low hERG inhibition. CDK9-IN-19 significantly inhibited tumor growth in the MV4-11 xenograft mouse model. CDK9-IN-19 can be used in studies of acute myeloid leukemia (AML) .

• Smiles :

  C(C)(=O)C1=C(C=2C(=CC(NC=3N=C(C(F)=CN3)C4=C(OC)C=C(F)C=C4)=CC2)OC1=O)N5CCOCC5

• Molecular Formula :

  C26H22F2N4O5

• Molecular Weight :

  508.47

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2479306-60-8