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JYQ-164

CAT: 0013-GTR19263135Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263135Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JYQ-164 is a small‐molecule inhibitor targeting human Parkinson’s disease protein 7 (PARK7/DJ‐1) with an IC50 value of 21 nM. It exerts its inhibitory effect by covalently and selectively targeting the key residue Cys106 of PARK7, and its inhibitory activity against PARK7 is approximately 5‐fold higher than that of the previously reported inhibitor JYQ‐88. JYQ-164 can be used in studies related to the mechanisms of Parkinson’s disease and cancer .
Smiles
O=C (NC1=NC2=C (CN (C (C3=CC (S (=O) (N4CCOCC4) =O) =CC=C3) =O) CC2) S1) [C@H]5CN (C#N) CC5
Molecular Formula
C23H26N6O5S2
Molecular Weight
530.62
Storage Conditions
-20°C
Notes
For research use only.

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