Products for Research Use Only

LZFPN-90

CAT: 0931-T209848-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209848-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
PD-1/PD-L1, Apoptosis, NAMPT
Related Pathways
Apoptosis, Immunology/Inflammation, Metabolism, Cell Cycle/Checkpoint
Bioactivity
LZFPN-90 (LZ90) is a dual-target compound aimed at NAMPT and PD-L1. It inhibits the interaction between PD-1/PD-L1 and NAMPT activity. LZFPN-90 suppresses cell growth in a NAMPT-dependent manner, blocking the cell cycle and subsequently inducing apoptosis. Additionally, LZFPN-90 exhibits target-dependent antitumor activity, impacting metabolic processes and the immune system.
Molecular Formula
C33H36N8O2S
Shipping Conditions
Ice Packs
Storage Temperature
-20°C