LZFPN-90

• Target:

  PD-1/PD-L1|||Apoptosis|||NAMPT

• Related Pathways:

  Apoptosis|||Immunology/Inflammation|||Metabolism|||Cell Cycle/Checkpoint

• Bioactivity:

  LZFPN-90 (LZ90) is a dual-target compound aimed at NAMPT and PD-L1. It inhibits the interaction between PD-1/PD-L1 and NAMPT activity. LZFPN-90 suppresses cell growth in a NAMPT-dependent manner, blocking the cell cycle and subsequently inducing apoptosis. Additionally, LZFPN-90 exhibits target-dependent antitumor activity, impacting metabolic processes and the immune system.

• Molecular Formula:

  C33H36N8O2S

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C