Products for Research Use Only

EGFR-IN-90

CAT: 0931-T82491-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T82491-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
EGFR
Related Pathways
JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
EGFR-IN-90 (compound 34), an orally active EGFR inhibitor, demonstrates potent activity against EGFRL858R/T790M/C797S with an IC50 of 5.1 nM and effectively inhibits the proliferation of the H1975-TM cell line carrying EGFRL858R/T790M/C797S mutations with an IC50 of 0.05 μM. Additionally, EGFR-IN-90 suppresses tumor growth in the H1975-TM xenograft tumor model [1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C