KI-CDK9d-32

CAT: 0931-MF-0115078-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0115078-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3054009-82-1
Target
C-Myc|||PROTACs|||CDK
Related Pathways
Cell Cycle/Checkpoint|||PROTAC
Bioactivity
KI-CDK9d-32 is a CDK9 PROTAC degrader with a DC50 of 0.89 nM. It facilitates the ubiquitination and degradation of CDK9, inhibits the MYC pathway, and disrupts nucleolar homeostasis. KI-CDK9d-32 demonstrates anticancer activity.
Smiles
O=C1C=2C(CN1C3C(=O)NC(=O)CC3)=CC(=CC2)N4CCN(CC5=CC=C(C(N[C@H]6C[C@H](NC=7N8C(N=C(CCC)C7)=CC=N8)CC6)=O)C=C5)CC4
Molecular Formula
C39H45N9O4
Molecular Weight
703.83
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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