KI-CDK9d-32

• Target:

  C-Myc|||PROTACs|||CDK

• Related Pathways:

  Cell Cycle/Checkpoint|||PROTAC

• Bioactivity:

  KI-CDK9d-32 is a CDK9 PROTAC degrader with a DC50 of 0.89 nM. It facilitates the ubiquitination and degradation of CDK9, inhibits the MYC pathway, and disrupts nucleolar homeostasis. KI-CDK9d-32 demonstrates anticancer activity.

• Smiles:

  O=C1C=2C(CN1C3C(=O)NC(=O)CC3)=CC(=CC2)N4CCN(CC5=CC=C(C(N[C@H]6C[C@H](NC=7N8C(N=C(CCC)C7)=CC=N8)CC6)=O)C=C5)CC4

• Molecular Formula:

  C39H45N9O4

• Molecular Weight:

  703.83

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3054009-82-1