Products for Research Use Only
RegisterLogin

BCX-3607

CAT: 0931-T207179-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T207179-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
885684-79-7
Target
Others
Related Pathways
Others
Bioactivity
BCX-3607 is an orally active tissue factor/factor VIIa (TF-FVIIa) inhibitor with an IC50 of 4 nM. By inhibiting the TF-FVIIa complex, it effectively blocks the extrinsic coagulation pathway and significantly prolongs prothrombin time (PT) . BCX-3607 exhibits higher selectivity for TF-FVIIa over other serine proteases like thrombin and FXa. It reduces thrombus weight and inflammation, offering dual anti-thrombotic and anti-inflammatory effects. BCX-3607 is applicable in research on thrombosis-related diseases.
Smiles
O=C(O)C1=CC(=CC=C1C=2C=CC(C=C)=CC2CNC3=NC=C(C=C3)C(=N)N)C(=O)NCC(C)C
Molecular Formula
C27H29N5O3
Molecular Weight
471.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Bcx-3607

a small molecule tissue factor/factor VIIa inhibitor with antithrombotic and anti-inflammatory effects; structure in first source

CAS Number885684-79-7
PubChem CID9912630
IUPAC Name2-[2-[[(5-carbamimidoyl-2-pyridinyl)amino]methyl]-4-ethenylphenyl]-5-(2-methylpropylcarbamoyl)benzoic acid
Molecular FormulaC27H29N5O3
Molecular Weight471.5
XLogP4.2
Topological Polar Surface Area141
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count10
Heavy Atom Count35
Formal Charge0
Complexity757
SMILES
CC(C)CNC(=O)C1=CC(=C(C=C1)C2=C(C=C(C=C2)C=C)CNC3=NC=C(C=C3)C(=N)N)C(=O)O
InChI
InChI=1S/C27H29N5O3/c1-4-17-5-8-21(20(11-17)15-31-24-10-7-19(14-30-24)25(28)29)22-9-6-18(12-23(22)27(34)35)26(33)32-13-16(2)3/h4-12,14,16H,1,13,15H2,2-3H3,(H3,28,29)(H,30,31)(H,32,33)(H,34,35)
InChIKey
HHFWQMFTPDFWLM-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Bcx-3607
CAS: 885684-79-7
CID: 9912630
Formula: C27H29N5O3
MW: 471.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight471.5
XLogP34.2
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count10
Exact Mass471.22703980
Monoisotopic Mass471.22703980
Topological Polar Surface Area141 Ų
Heavy Atom Count35
Formal Charge0
Complexity757
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T73347-01BCX-1898
T13568-01BCX 1470
TYD-03414-01Bcx-1812-CoA
T13568L-01BCX 1470 hydrochloride
T13567-01BCX 1470 methanesulfonate
T7409-01360A
T69076-01S-3608
T9530-01W 36017
T13504-01360A iodide
T4263-01BAY 61-3606

Alternative Products

CatalogName
HY-172905BCX-3607
TRC-B119190-10MGBCX 4430
MBS5767989BCX 1470
GTR19155057-01BCX-4430
GTR19212187-01BCX-1898
HY-106421BCX-5
MBS3603470-01BCX-1470
HY-CE01217Bcx-1812-CoA
MBS3603471-01BCX-1470 methanesulfonate
MBS386704-01BCX 1470 methanesulfonate

Popular Products