Products for Research Use Only
RegisterLogin

NLRP3-IN-75

CAT: 0931-T206986-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T206986-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
NF-κB, NOD-like Receptor (NLR), Interleukin
Related Pathways
Immunology/Inflammation, NF-κB
Bioactivity
NLRP3-IN-75 is an orally effective inhibitor of NLRP3, capable of suppressing IL-1β secretion with an IC50 of 23 nM. It selectively inhibits NLRP3 activation by disrupting inflammasome assembly without affecting the assembly of NLRC4 or AIM2 inflammasomes. NLRP3-IN-75 demonstrates excellent anti-inflammatory effects in models of acute peritonitis, diabetic nephropathy, and inflammatory bowel disease (IBD) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T212221-01NLRP3-IN-82
T210731-01NLRP3-IN-81
T210618-01NLRP3-IN-79
T209813-01NLRP3-IN-36
T209812-01NLRP3-IN-35
T206735-01NLRP3-IN-78
T206561-01NLRP3-IN-73
T204736-01NLRP3-IN-68
T204006-01NLRP3 IN 7n
T203150-01NLRP3-IN-65

Alternative Products

CatalogName
GTR19258114-01NLRP3-IN-75
QY-E06005Human NLRP3 Inflammasome (NLRP3)
MBS8534011-01NLRP3
BA6124-10NLRP3-IN-17
BA6050-10NLRP3-IN-25

Popular Products