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LZ-007

CAT: 0013-GTR19241757-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241757-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LZ-007 is a potent FXR agonist, demonstrating EC50 values of 51 nM in TR-FRET and 76 nM in HepG2 cells. It shows favorable pharmacokinetics in rats and has been shown to ameliorate diet- and CCl4-induced metabolic dysfunction-associated steatohepatitis in mouse models.
CAS Number
2920000-23-1
Field of Research
Metabolism Research
Smiles
O=C (O) C1=CC=C (OCC2CCN (CC=3C (=NOC3C (C) C) C=4C=CC=CC4OC (F) (F) F) CC2) C=C1
Molecular Formula
C27H29F3N2O5
Molecular Weight
518.53
Storage Conditions
-20°C
Notes
For research use only.

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