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SOF-436

CAT: 0931-T206673-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206673-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2224491-20-5
Target
Ras
Related Pathways
GPCR/G Protein, MAPK
Bioactivity
SOF-436 is a KRAS inhibitor that can suppress SOS1-mediated KRAS nucleotide exchange (IC50 = 60 μM) and inhibit the interaction between KRAS and the effector protein RAF. SOF-436 is applicable to cancer research.
Smiles
O=S(=O)(F)C1=CC=CC(=C1)S(=O)(=O)NC2=CC=C(C(F)=C2)C3CC3
Molecular Formula
C15H13F2NO4S2
Molecular Weight
373.395
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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