SOF-436

• Target :

  Ras

• Related Pathways :

  GPCR/G Protein|||MAPK

• Bioactivity :

  SOF-436 is a KRAS inhibitor that can suppress SOS1-mediated KRAS nucleotide exchange (IC50 = 60 ?M) and inhibit the interaction between KRAS and the effector protein RAF. SOF-436 is applicable to cancer research.

• Smiles :

  O=S(=O)(F)C1=CC=CC(=C1)S(=O)(=O)NC2=CC=C(C(F)=C2)C3CC3

• Molecular Formula :

  C15H13F2NO4S2

• Molecular Weight :

  373.395

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2224491-20-5