TAK-632

• Target:

  PDGFR|||Aurora Kinase|||FGFR|||Raf

• Related Pathways:

  Tyrosine Kinase/Adaptors|||MAPK|||Chromatin/Epigenetic|||Angiogenesis|||Cell Cycle/Checkpoint

• Purity:

  0.995

• Bioactivity:

  TAK-632, a potent pan-Raf inhibitor (GenScript, 2020), is characterized by its molecular weight [M] for [C 22 H 19 FN 2 O 2] of 362.4 by LC-MS, with a purity of 99% (HPLC) . The compound exhibits white to off-white solid form and has a melting point [M] ranging from 178°C to 182°C (GenScript, 2020) . Its solubility profile includes DMSO, in which it is soluble to 100mM (GenScript, 2020) .

• Smiles:

  Fc1ccc(Oc2ccc3nc(NC(=O)C4CC4)sc3c2C#N)cc1NC(=O)Cc1cccc(c1)C(F)(F)F

• Molecular Formula:

  C27H18F4N4O3S

• Molecular Weight:

  554.52

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1228591-30-7