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Cath-L-dBET1

CAT: 0931-T206243-01Size: 10 mgDry Ice: NoHazardous: No
CAT#: T206243-01Size: 10 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Epigenetic Reader Domain|||PROTACs
Related Pathways
Chromatin/Epigenetic|||PROTAC
Bioactivity
Cath-L-dBET1 is a PROTAC degrader targeting BRD4. It has an IC50 value of 2.8 ?M in MDA-MB-231 cells. Activated by cathepsin L (Cath-L), Cath-L-dBET1 recruits E3 ubiquitin ligase to degrade BRD4 via the ubiquitin-proteasome system. Hyp-dBET1 is applicable for antitumor research.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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