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DBET1

CAT: 0931-T4495-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T4495-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1799711-21-9
Target
Epigenetic Reader Domain, PROTACs
Related Pathways
PROTAC, Chromatin/Epigenetic
Purity
0.993
Bioactivity
DBET1 is a hybrid molecule that combines (+) -JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apoptosis.
Smiles
CC=1C2=C(N3C([C@H](CC(NCCCCNC(COC4=C5C(C(=O)N(C5=O)C6C(=O)NC(=O)CC6)=CC=C4)=O)=O)N=C2C7=CC=C(Cl)C=C7)=NN=C3C)SC1C
Molecular Formula
C38H37ClN8O7S
Molecular Weight
785.27
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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