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PPARγ agonist 17

CAT: 0931-T206082-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206082-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3054652-58-0
Target
PPAR
Related Pathways
DNA Damage/DNA Repair, Metabolism
Bioactivity
PPARγ agonist17 (Compound C1) is an orally active PPARγ agonist. It enhances PPARγ activity, arrests the cell cycle of HT-29 cells at the G2/M phase, inhibits cell migration, and induces apoptosis. PPARγ agonist17 exhibits broad-spectrum antiproliferative activity against cancer cells with relatively low toxicity to normal cells and does not cross the blood-brain barrier.
Smiles
C[C@]12[C@@]3(C)C([C@]4([C@@](C)(CC3)CC[C@@](C(O)=O)(C)C4)[H])=CC(=O)[C@@]1([C@]5(C)[C@@](CC2)(C(C)(C)[C@@H](OC(CC6=CC(NC(COC7=C(C)C=CC(C)=C7)=O)=CC=C6)=O)CC5)[H])[H]
Molecular Formula
C48H63NO7
Molecular Weight
766.016
Shipping Conditions
Ice Packs
Storage Temperature
-20°C