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PT-129

CAT: 0931-T205713-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T205713-01Size:10 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
GTPase
Related Pathways
GPCR/G Protein
Bioactivity
PT-129 is a PROTAC degrader targeting the NTF2 domain of G3BP1/2, capable of inhibiting and degrading stress granules in stressed cells, disrupting ATF4 trafficking, and suppressing fibroblast-mediated cancer cell proliferation.
Smiles
O=C(N(C1C(NC(CC1)=O)=O)C2=O)C3=C2C=CC=C3NCCOCCOCCOCCC(NC4=CC=C(NC([C@H](CC5=CC=CC=C5)NS(=O)(CC(N6C(C=CC=C7)=C7C=N6)=O)=O)=O)C=C4)=O
Molecular Formula
C46H48N8O12S
Molecular Weight
936.98
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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